An article by Healthline states:
1. Artificial sweeteners affect the gut microbiome in mice.
2. The affected gut microbiome raises your blood sugar level.
Unfortunately, one conclusion in the Healthline article regarding insulin response after consumption of sucralose is incorrect. The article states: “However, results are mixed and other human studies have shown no effect (10).” The article referenced used intragastric infusion, in other words they used a catheter to deliver the sucralose, thus bypassing the taste buds. While I don't know if this was intentional, according to examine.com, there is a prevalence of misinformation on the web.
Insulin level rises when taste buds sense anything sweet, regardless of the calorie content.1